Dengue Fever Research Today is a free monthly online journal that collates and summarizes the latest research about Dengue Fever, including details on symptoms, risk factors, diagnosis, treatment, prevention.

Dengue hemorrhagic fever and acute hepatitis: a case report.

Mourão MP, Lacerda MV, Bastos Mde S, Albuquerque BC, Alecrim WD

Tropical Medicine Foundation of Amazonas, Laboratory of Arbovirology, University of the State of Amazonas, Av. Pedro Texeira 25, Planalto, 69040-000 Manaus, Amazonas, Brazil. mpmourao@uol.com.br

Dengue fever is the world's most important viral hemorrhagic fever disease, the most geographically wide-spread of the arthropod-born viruses, and it causes a wide clinical spectrum of disease. We report a case of dengue hemorrhagic fever complicated by acute hepatitis. The initial picture of classical dengue fever was followed by painful liver enlargement, vomiting, hematemesis, epistaxis and diarrhea. Severe liver injury was detected by laboratory investigation, according to a syndromic surveillance protocol, expressed in a self-limiting pattern and the patient had a complete recovery. The serological tests for hepatitis and yellow fever viruses were negative. MAC-ELISA for dengue was positive.

Published 9 May 2005 in Braz J Infect Dis, 8(6): 461-4.
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